The beaten Assassin walked through the gates of Monteriggioni before collapsing onto the ground, followed by Cesare and his allies; including his sister, Lucrezia, Micheletto Corella, Baron Octavian de Valois, and Juan Borgia.
Cesare sheathed his sword and spoke out to Ezio himself, who had seen the Borgia's entrance and was running across the rooftops to aid Mario. The Borgia Captain General spoke of how the Pope had told him of the Assassins and Apple. He then turned and grabbed the Baron de Valois' firearm from him, a pistol that Ezio's good friend, Leonardo da Vinci, had been forced to fashion for them.
Cesare stated that there had been too much bloodshed on both sides, and that a "cleansing was in order". Raising the pistol into the air, Cesare "invited" Ezio to come and face him in Rome, and killed Mario with a shot from the firearm.
Ezio was then shot down and wounded by a team of arquebusiers. Cesare immediately had Mario decapitated, his severed head placed on a pike. During Ezio's escape, Cesare showed Mario's head to him, exclaiming that he would kill him next. With Monteriggioni in ruins, Cesare and his army returned to Rome with their prize.
- Oliverotto：“I never wished you any harm, Cesare. It was entirely Vitellozzo's plan!”
- 切萨雷：“Ha! Your sacrifice will prove invaluable to me.”
- ——Oliverotto pleading to Cesare before being killed by Micheletto, 1500.
Following the Siege of Monteriggioni, Cesare commanded Ramiro d'Orco, Vitellozzo Vitelli and Oliverotto da Fermo to lead his armies into Romagna and claim it for their Borgia master. However, all three generals eventually rebelled against Cesare, to which he responded by butchering Ramiro.
His death panicked both Oliverotto and Vitellozzo, forcing them both to re-enter Cesare's service, after he accepted their every demand to return without consequences for the rebellion. However, with Romagna his, Cesare no longer required their service. Months later, Cesare threw a "dinner" in Vitellozzo and Oliverotto's honor.
Once both generals arrived at the location Cesare given, he spoke out to them, thanking them for handing Romagna to him, but claimed it was time to shed his "bloody gloves".
As several Papal Guards arrived at Cesare's side, they both realized that they had entered an ambush, thus they both charged into a fray immediately. Though outnumbered, both Oliverotto and Vitellozzo overpowered them. Cesare then armed himself with a crossbow, and as a surviving Papal Guard wounded Vitellozzo, Cesare fired the bolt at Oliverotto's chest.
Several hours later, both Vitellozzo and Oliverotto regained consciousness, recovering from their wounds. As they woke up, they realized that they were chained back-to-back. In front of them Cesare stood, aside Micheletto Corella. Though Oliverotto blamed Vitellozzo for the conspiracy against him, Cesare ultimately ordered Micheletto to strangle both Viellozzo and Oliverotto back-to-back, claiming their "sacrifice" was invaluable to him.
By 1500, Cesare had Rome under his iron fist as the commander of the Papal army, though he and his father occasionally disagreed on his choices. He used Borgia towers and their captains to keep control over the five districts of Rome, as he was often away for extended periods of time to oversee the advancement of his army, in a bid to unite all of Italy under his rule.
During Ezio's infiltration of the Castel Sant'Angelo in late June 1501, Cesare was seen at the stables conversing with his three generals about their plans, where he told them to play along with his father's "tired old men's club," but to remember who they really served.
Subsequently, he shared a romantic moment with his sister. Cesare asked if their father had considered the funds requested by his banker, though she claimed he was away from the Castel and may need convincing. Cesare then left the Castel for Romagna to continue his campaign.
In 1502, Cesare continued to make use of Leonardo da Vinci's intellect, forcing him to design several war machines for his army. However, all of Leonardo's creations were eventually stolen and destroyed by Ezio Auditore, in secret, at Leonardo's own request.
In 1503, Cesare attended Juan Borgia's pagan party, where he gave a brief speech on a soon to be united Italy. After Cesare commanded the party to begin, Rodrigo reminded him that they had not agreed to conquer Italy. However, Cesare stated that he was now in control, although not officially, and simply told his father to enjoy himself.
Later that year, Cesare had his close friend, Francesco Troche, assassinated by Micheletto Corella, for telling his brother of Cesare's intentions for Romagna. Cesare then ordered Micheletto to assassinate the actor Pietro Rossi, Lucrezia's secret lover.
In August of 1503, due to the interference of the Roman Assassins, Cesare's army and funds had significantly diminished. Enraged, Cesare confronted Rodrigo, demanding to know what had happened. There, Cesare and Rodrigo argued over the former's insatiable lust for power. Rodrigo commented that he had given Cesare all he had, yet his son was never satisfied.
Cesare demanded that his father give him the Apple of Eden, but Rodrigo refused. At this point, Lucrezia barged in, crying out to her brother that their father was attempting to poison him with the bowl of apples he had left out.
An outraged Cesare responded by charging Rodrigo and shoving the poisoned apple down his throat, suffocating him. Cesare then demanded the Apple's whereabouts from Lucrezia, who confessed under much pressure. However, Ezio beat Cesare to the Basilica di San Pietro, the Apple's location, and retrieved the Piece of Eden before him.
Cesare's rule met a downward spiral from there. As a final stab from his father, Cesare had consumed enough of the poison to leave him weak for months. While he recovered, Ezio and the other Assassins used the Apple to dwindle his remaining forces, while the Vatican meanwhile fully rejected Cesare's request for support, seeing the Borgia's money as "tainted."
Cesare sent Micheletto to retrieve his armies from the battlefield in order to reclaim Rome, however, he was confronted by the highest-ranking Assassins as he awaited his return. As the last of his followers fell, Fabio Orsini arrived with the Papal Guard and a warrant for Cesare's arrest by the order of Pope Julius II. Cesare was taken away, imprisoned, and later exiled to Spain.
Subsequently following his arrest, Cesare was imprisoned in the Castel Sant'Angelo. However, he was able to escape the prison and flee. Though Cesare was later recaptured, Pope Julius II concluded that Cesare needed to be transferred to a more secure prison, and had the Templar moved to the Castillo de la Mota, Aragon, in Spain. Though Ezio had intended to kill Cesare despite his imprisonment, he was unaware of where Cesare had been transferred. He, Machiavelli, and Leonardo began tracking him down, while Micheletto, who had evaded imprisonment and remained loyal to Cesare, planned for his master's escape.
In 1506, Micheletto bribed a prison guard at the Castillo. Having had rope smuggled in for him, Cesare climbed down from his window and sneaked past the main gate in his stolen guard uniform. Meeting with Micheletto, he was informed that Ezio was currently tracking him, though he said nothing on the matter. Micheletto then told his master that he had made arrangements in Valencia. With this, Cesare made his escape, and rode to Valencia with Micheletto.
- 切萨雷：“You got me out of La Mota, sure, and you up my hopes. But now look where you have got me!”
- 米凯莱托：“Master, all my men are dead. I have done what I could.”
- 切萨雷：“And failed!”
- ——Cesare before bursting into a tirade about Micheletto and killing him, Valencia, 1506.[来源]
Following his escape, Cesare began to rebuild his forces in Valencia, with men volunteering to enter his service and setting up a large military encampment. Whilst Cesare was raising a small army, he spent most of his time coordinating battle tactics at the Lone Wolf Inn. Ezio and Machiavelli soon discovered this, however, and were able to destroy the encampment and twelve ships with Leonardo's hand-held bombs.
Later, they spied on him from the roof of the Lone Wolf. Cesare blamed Micheletto for the Assassins' attack, and insulted him as a dog, remarking that he should find somewhere to die. During his tirade against Micheletto, Cesare claimed that he would cross the borders and join his brother-in-law, King John III of Navarre to seek his aid.
Though Micheletto begged Cesare, and reminded him of his loyal service, Cesare continued to insult him. However, this rebounded on Cesare, as Micheletto, realizing how much his service meant to his ungrateful master, attempted to murder Cesare by strangling him. However, Cesare was able to shove Micheletto away and shoot him in the head, killing him. Ezio and Machiavelli, who had watched the scene unfold, made a noise from above. Cesare, who heard this, fired his rifle and wounded Machiavelli.
- “I will lead mankind into a new world! You cannot kill me! No man can murder me!”
- ——Cesare Borgia's last words, 1507.[来源]
In March of 1507, Cesare tried to regain his lost honor by commandeering John III's vast army during the Siege of Viana, after which, should he be victorious, he would regain the support of the French. However, unbeknownst to him, Ezio caught wind of Cesare's involvement in the battle and set out for Viana.
During the siege, Ezio located and charged Cesare on the battlefield, though Cesare held him back just long enough to dodge his Hidden Blade and flee. Ezio's pursuit was delayed by several cannonball impacts that stunned him, and incapacitated the other soldiers in the area.
Ezio soon caught up to him on the outskirts of the castle walls, where Cesare had his soldiers kill a civilian woman, who was crying for him to help her son, who had been injured. Ezio eventually faced Cesare on the walls of Viana's Castle and fought against him, with Cesare wielding a sword and a pistol.
Though Cesare attacked with speed and skill, while also periodically calling reinforcing troops, Ezio nevertheless defeated him, eventually pinning him to the ground. When Cesare vowed not to die at the hands of man, Ezio declared that he would leave Cesare "in the hands of Fate," and threw him off of the castle wall to his death.
- 切萨雷: 王座属于我!
- 埃齐奥: 对某种东西的渴求并不会使他变成你的.
- 切萨雷: 你知道什么?
- 埃齐奥: 真正的统治者会将权力交给他的人民.
- 埃齐奥: Che nessuno ricordi il tuo nome. ( 但愿没人记得你的恶名.) Requiescat in pace. (安息吧.)
- 切萨雷: 你无法杀死我. 没有人类可以杀死我!
- 埃齐奥: 那么我就把你交与命运之手.
- 他的名字"Cesare" 在意大利语中读作"Cheh-ser-ay." 就是凯撒。巧合的是，乔瓦尼·博吉亚曾因出血效应而将切萨雷误认为盖乌斯·尤利乌斯·凯撒而试图刺杀他。
- 切萨雷认为流血事件是一种“清洗”，这与 Abstergo名称的本意的惊人地相似。在拉丁语中 Abstergo的意思是“清洗”。